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World J Gastroenterol. Jan 21, 2010; 16(3): 384-391
Published online Jan 21, 2010. doi: 10.3748/wjg.v16.i3.384
Published online Jan 21, 2010. doi: 10.3748/wjg.v16.i3.384
Figure 4 Liver histopathology and transferase-mediated dUTP nick end-labeling (TUNEL) assay.
APAP was given intraperitoneally with a single dose of 300 mg/kg. GM was given orally with a single dose of 200 mg/kg. A and E: Normal group; B and F: APAP group; C and G: APAP plus GM 200 mg/kg; D and H: Only GM 200 mg/kg. Upper panels stand for HE staining and the lower panels for TUNEL assay. The regions by black arrows in the upper figures indicate the hepatocyte necrosis or hepatocyte degeneration; the regions by red arrows in the lower figures indicate the TUNEL-positive apoptotic cells (× 100 magnification).
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Citation: Wang AY, Lian LH, Jiang YZ, Wu YL, Nan JX.
Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in micevia inhibiting JNK/ERK MAPK pathway. World J Gastroenterol 2010; 16(3): 384-391 - URL: https://www.wjgnet.com/1007-9327/full/v16/i3/384.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i3.384