Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway

Figure 2 Protective effects of GM on serum biochemical parameters after acetaminophen (APAP) administration. Mice were intraperitoneally injected with APAP (300 mg/kg body weight). GM (200, 100 or 50 mg/kg body weight) was orally administered at 2 h before APAP injection. All data are presented as mean ± SD, n = 10/group. ^aP < 0.05, ^bP < 0.01, significantly different when compared with normal controls. ^cP < 0.05, ^dP < 0.01, ^eP < 0.001 significantly different when compared with APAP alone group.