HBV genotype C is independently associated with cirrhosis in community-based population

doi:10.3748/wjg.v16.i3.379

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 21, 2010; 16(3): 379-383
Published online Jan 21, 2010. doi: 10.3748/wjg.v16.i3.379

Table 2 Univariate and multivariate regression analyses for the risk factors of probable liver cirrhosis in the 595 HBeAg negative subjects infected with HBV

Variables	Controls (n = 513)	Cases (n = 82)	OR (95% CI)	AOR (95% CI)
Age (yr)
< 45	284 (55.4)	31 (37.8)
≥ 45	229 (44.6)	51 (62.2)	2.04 (1.26-3.29)	1.81 (1.10-2.99)
Sex
Female	235 (45.8)	25 (30.5)
Male	278 (54.2)	57 (69.5)	1.93 (1.17-3.18)	1.74 (1.03-2.95)
ALT (U/L)
≤ 45	473 (92.2)	66 (80.5)
> 45	40 (7.8)	16 (12.9)	2.87 (1.52-5.41)	2.98 (1.48-5.99)
Viral load (Log₁₀ copies/mL)
< 4	432 (84.2)	67 (81.7)
≥ 4	81 (15.8)	15 (18.3)	1.19 (0.65-2.19)	1.06 (0.54-2.08)
Genotype
B	170 (34.4)	16 (20.8)
C	324 (65.6)	61 (79.2)	2.00 (1.12-3.58)	2.30 (1.26-4.19)

AOR: Adjusted odds ratio; OR: Odds ratio.

Citation: Yin JH, Zhao J, Zhang HW, Xie JX, Li WP, Xu GZ, Shen J, Dong HJ, Zhang J, Wang L, Han JK, Wang HY, Cao GW. HBV genotype C is independently associated with cirrhosis in community-based population. World J Gastroenterol 2010; 16(3): 379-383
URL: https://www.wjgnet.com/1007-9327/full/v16/i3/379.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i3.379