Body composition changes after transjugular intrahepatic portosystemic shunt in patients with cirrhosis

Table 1 Modification of values studied in 21 patients (mean ± SD)

Variable	Basal Pre-TIPS	After 52 wk	P
HVPG (mmHg)	15.8 ± 4.8	6.0 ± 2.1	< 0.001
Bilirubin (mg/dL)	1.26 ± 1.11	2.85 ± 2.29	0.017
Creatinine (mg/dL)	1.02 ± 0.56	1.14 ± 0.61	0.18
Albumin (g/L)	31.3 ± 7.7	33.0 ± 7.7	0.586
GEC (mmol/min)	1.79 ± 0.48	1.61 ± 0.41	0.081
MELD (score) (n = 18)1	11 (6)	13 (7)	0.804
Blood glucose (mmol/L)	5.8 ± 1.5	6.3 ± 1.6	0.345
Plasma insulin (pmol/L)	128.9 ± 84.0	182.9 ± 100.6	0.024
HOMA-β	269 ± 409	233 ± 108	0.700
HOMA-IR	5.04 ± 4.07	7.82 ± 5.89	0.028
BMI (kg/m2)	26.2 ± 5.8	27.4 ± 5.6	0.172
FFA (mmol/L)	0.54 ± 0.23	0.89 ± 0.44	0.013
Creatinine (mg/dL)	0.98 ± 0.52	0.83 ± 0.34	0.053
Fat mass (%)	29.4 ± 7.7	27.8 ± 8.7	0.278
Fat mass (kg)	23.4 ± 10.5	22.9 ± 10.0	0.812
Dry lean mass (kg)	14.0 ± 5.8	14.8 ± 5.0	0.115
TBW (L)	32.3 ± 9.6	43.3 ± 10.3	0.017

¹Median (interquartile range). Values were obtained 2 wk before (Basal) and 52 wk after TIPS insertion. P < 0.05 is considered statically significant. TIPS: Transjugular intrahepatic porto-systemic shunt; HVPG: Hepatic venous pressure gradient; GEC: Galactose elimination capacity; MELD: Model for end-stage liver disease; HOMA: Homeostasis model assessment; IR: Insulin resistance; BMI: Body mass index; FFA: Free fatty acids; TBW: Total body water.