Transcatheter arterial chemoembolization with a fine-powder formulation of cisplatin for hepatocellular carcinoma

Table 1 Patient characteristics

Characteristics	DDPH group	ADM group	P value
No. of patients	76	88
Age (yr) [median, (range)]	67 (32-87)	69 (21-90)	0.093
Gender (male/female)	57/19	52/36	0.031
Etiology (HBV/HCV/NBNC)	11/50/15	8/64/16	0.508
Child-Pugh classification (A/B/C)	47/26/3	45/36/7	0.303
TNM classification (I-II/III-IV)	10/66	24/64	0.026
Tumor size ( ≤ 3.0/> 3.0 cm)	21/55	30/58	0.373
Number of tumors (1-3/≥ 4)	35/41	46/42	0.427
PVTT (Vp0-2 /Vp3)	62/14	80/8	0.080
Total bilirubin ( ≤ 1.5/> 1.5 mg/dL)	66/10	75/13	0.906
Albumin ( ≤ 3.5/> 3.5 g/dL)	38/38	45/42	0.822
AFP ( ≤ 1000/> 1000 ng/mL)	68/8	79/8	0.776
DCP ( ≤ 1000/> 1000 mAU/mL)	59/14	73/14	0.609

Data are expressed as median with range values, or the number of patients. The stages of HCC by TNM classification are clustered into two groups (I-II and III-IV). The tumor characteristics and other parameters are classified as follows: tumor size: ≤ 3.0, > 3.0 cm; tumor number: 1-3, > 4; extent of PVTT: Vp 0-2, and Vp 3; serum bilirubin: ≤ 1.5, > 1.5 mg/dL; serum albumin: ≤ 3.5, > 3.5 g/dL; serum AFP levels: ≤ 1000, > 1000 ng/mL. Serum DCP levels: ≤ 1000, > 1000 mAU/mL. HBV: Hepatitis B virus; HCV: Hepatitis C virus; NBNC: Negative for hepatitis B surface antigen and HCV antibody; PVTT: Portal vein tumor thrombosis; AFP: α-fetoprotein; DCP: Des-γ-carboxy prothrombin; DDPH group: Using a suspension of DDPH in lipiodol (LPD); ADM group: With an emulsion of doxorubicin (ADM) with LPD.