Promoter hypermethylation and loss of CD133 gene expression in colorectal cancers

doi:10.3748/wjg.v16.i25.3153

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2010; 16(25): 3153-3160
Published online Jul 7, 2010. doi: 10.3748/wjg.v16.i25.3153

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Figure 4 Analysis of methylation status of promoter CpG islands of CD133 by clonal sequencing. A: Representative sequence diagrams of DNA sequencing analysis in (a) HT-29 (unmethylated) and (b) SW480 (methylated) cell lines. M: Methylated site; U: Unmethylated site; B: DNA sequencing analysis of 32 CpG dinucleotides. The numbers at the top show the CpG sites of amplified DNA by bisulfite sequencing primers. Circle represents CpG dinucleotides; closed circle: Methylation; open circle: Unmethylation.

Citation: Jeon YK, Kim SH, Choi SH, Kim KH, Yoo BC, Ku JL, Park JG. Promoter hypermethylation and loss of CD133 gene expression in colorectal cancers. World J Gastroenterol 2010; 16(25): 3153-3160
URL: https://www.wjgnet.com/1007-9327/full/v16/i25/3153.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i25.3153