Simultaneous detection of different serum pepsinogens and its primary application

Table 2 Serum PG level and PG I/PG II ratio in healthy controls and patients with duodenal ulcer, gastric ulcer, atrophic gastritis, superficial gastritis and gastric cancer (mean ± SD)

Diagnosis	n	Age (yr)	PG I (μg/L)	PG II (μg/L)	PG I/PG II ratio
Healthy controls	500	41.5 ± 18.8	150.3 ± 45.1	10.4 ± 8.4	14.5 ± 4.3
Patients with duodenal ulcer	112	43 ± 14.2	252.9 ± 84.5d	18.4 ± 16.0d	13.7 ± 8.0
Patients with gastric ulcer	44	37 ± 11.2	221.2 ± 91.7d	15.6 ± 12.4b	14.2 ± 7.1
Patients with atrophic gastritis	21	48 ± 9.7	89.5 ± 51.2d	12.9 ± 9.39	6.9 ± 6.2b
Patients with superficial gastritis	76	35 ± 7.4	175.3 ± 45.8a	12.7 ± 10.1	13.8 ± 5.3
Patients with gastric cancer	126	55 ± 12.2	157.1 ± 81.9	15.6 ± 14.4b	13.4 ± 7.8

^aP < 0.05,

^bP < 0.01,

^dP < 0.001 vs healthy controls.