Glycated hemoglobin and antidiabetic strategies as risk factors for hepatocellular carcinoma

Table 3 Association of DM2 with HCC: results of multivariate analyses using controls and LC subjects as comparison groups

	OR	95% CI	P
Control group
Age ≥ 65 yr	0.873	0.606-1.259	0.4675
BMI ≥ 25 kg/m2	1.048	0.769-1.426	0.7681
Alcohol abuse	22.069	13.749-35.425	< 0.0001
DM2	2.507	1.703-3.692	< 0.0001
LC group
Age ≥ 65 yr	2.457	1.855-3.252	< 0.0001
BMI ≥ 25 kg/m2	1.560	1.197-2.032	0.0010
HBV positive	2.372	1.363-4.127	0.0022
HCV positive	2.783	1.896-4.084	< 0.0001
Alcohol abuse	1.937	1.318-2.845	0.0008
ALT ≥ 53 IU/L	0.919	0.672-1.256	0.5951
DM2	1.456	1.072-1.979	0.0162

BMI: Body mass index; OR: Odds ratio; 95% CI: 95% confidence interval; ALT: Alanine transaminase.