Antiproliferative effect of somatostatin analogs in gastroenteropancreatic neuroendocrine tumors

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Jun 28, 2010 (publication date) through Nov 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 28, 2010; 16(24): 2963-2970
Published online Jun 28, 2010. doi: 10.3748/wjg.v16.i24.2963

Table 1 Receptor binding affinities of somatostatin, octreotide and lanreotide

	sst₁	sst₂	sst₃	sst₄	sst₅
Receptor binding affinity (IC₅₀ nmol/L)
Somatostatin[12]	0.93	0.15	0.56	1.50	0.29
Octreotide[12]	280.00	0.38	7.10	> 1000	6.30
Lanreotide[13]	> 1000	0.80	107	> 1000	5.20

Citation: Strosberg J, Kvols L. Antiproliferative effect of somatostatin analogs in gastroenteropancreatic neuroendocrine tumors. World J Gastroenterol 2010; 16(24): 2963-2970
URL: https://www.wjgnet.com/1007-9327/full/v16/i24/2963.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i24.2963