Fixation methods for electron microscopy of human and other liver

Figure 4 Summary of the different steps in the preparation of liver tissue after aldehyde fixation (top figure) and the subsequent tissue sample preparation steps for the different modes of microscopy (bottom figure). Good laboratory practice should involve all three visualization modes in order to collect fine structural and topological data, together with insights into the interior of the sample. Left: SEM; Middle: Light microscopy (LM); Right: TEM.