Liver myofibroblasts activate protein C and respond to activated protein C

Figure 4 Human liver myofibroblasts can generate APC from PC. Supernatants were collected and incubated with an APC chromogenic substrate. The graph shows the optical density at 405 nmol/L, which resulted from cleavage of the substrate, which was proportional to the amount of APC generated. It represents the mean of two separate experiments.