Chronic niacin overload may be involved in the increased prevalence of obesity in US children

Figure 2 Dynamic effect of nicotinamide on plasma H₂O₂ level and glucose metabolism. A-E: Dynamic changes in the concentrations of plasma nicotinamide (NM), N¹-methylnicotinamide (NMN), H₂O₂, insulin and blood glucose in C-OGTT and NM-OGTT (co-administration of 300 mg nicotinamide and 75 g glucose). For each point, n = 5. Values represent mean ± SD, ^aP < 0.05, ^bP < 0.01 vs C-OGTT.