Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines

Table 4 Bax/Bcl-2 ratios of the four caged xanthone-treated and non treated CCA cell lines

Compounds	Bax/Bcl-2 ratio
	KKU-100 (h)				KKU-M156 (h)
	0	12	24	48	0	12	24	48
Isomorellinol	0.98	1.58	1.98	120	0.73	1.04	1.43	41.40
Forbesione	1.02	1.93	2.35	2.91	1.53	2.38	5.12	7.02
Gambogic acid	0.81	1.51	3.42	7.00	0.43	0.72	1.83	3.14
Isomorellin	0.98	1.98	3.12	5.20	0.56	0.70	1.00	1.90

Data are expressed as ratio of mean of protein expression level of Bax to Bcl-2 in control and the caged xanthone-treated CCA cell lines.