Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines

Table 2 Concentrations of four caged xanthones and doxorubicin causing a 50% inhibitory effect (IC₅₀) in cell proliferation

Cells	IC50 values (μmol/L)
	Isomorellin	Isomorellinol	Forbesione	Gambogic acid	Doxorubicin
KKU-100	0.11 ± 0.004	2.2 ± 0.33	0.15 ± 0.007	2.64 ± 1.29	0.66 ± 0.001
KKU-M156	0.12 ± 0.005	0.43 ± 0.06	0.02 ± 0.002	0.03 ± 0.004	0.36 ± 0.001
PBMC	> 88 × 104	59 ± 2.9	59.5 ± 1.0	11 ± 3	ND

Data are mean ± SE of three independent experiments. ND: Not detected.