Differentiation of focal liver lesions using three-dimensional ultrasonography: Retrospective and prospective studies

Table 2 Diagnostic criteria for focal liver lesions depicted by CE 2D US

Lesion	Enhancement patterns
	Early phase	Middle phase	Late phase
HCC	Intratumoral vessels with early homogeneous or heterogeneous enhancement, or intratumoral vessels alone	Homogeneous or heterogeneous enhancement	Hypoechoic lesion
Metastasis	Peritumoral vessels with early peripheral ring like enhancement	Peripheral ring like enhancement or perfusion defect	Hypoechoic lesion
Hemangioma	Peripheral nodular enhancement	Peripheral nodular enhancement, with centripetal progression	Isoechoic lesion, with centripetal progression
FNH	Spoke-wheel arteries with early homogeneous enhancement	Homogeneous enhancement	Isoechoic lesion with central scar

CE: Contrast-enhanced; 2D US: Two-dimensional ultrasonography.