Postoperative ileus: Impact of pharmacological treatment, laparoscopic surgery and enhanced recovery pathways

Table 2 Effect of interventions to improve gastrointestinal recovery and reduce LOS

Trials	Type of study	Intervention	Improvement passage flatus	Improvement first bowel movement	Decrease in LOS
Noble et al[52]	Meta analysis	Chewing gum	14 h	23 h	1.1 d
Delaney et al[54]	Pooled analysis	Alvimopan	12 h1 (6 mg)	15 h2 (6 mg)	18.4 h3
			15 h1 (12 mg)	18 h2 (12 mg)
Delaney et al[28]	Observational multicenter study	Laparoscopic surgery	NA	0.7 d2	1.7 d3
Walter et al[69]	Meta analysis	ERP	NA	NA	3.64 d

¹Defined as GI³;

²Defined as GI²;

³Discharge order written. Standard elective open colorectal resection is usually associated with LOS of 8-12 d. Pharmacological treatment, laparoscopic surgery and ERP have substantially decreased LOS after surgery. LOS: Length of stay; ERP: Enhanced recovery pathways; NA: Not available.