Molecular determinants of the antitumor effects of trichostatin A in pancreatic cancer cells

Figure 2 Effects of TSA on the BrdU incorporation of PC cell lines. BxPC-3, AsPC-1 and CAPAN-1 cells were treated with TSA as indicated for 24 h, before DNA synthesis was assessed with the BrdU incorporation assay. 100% BrdU incorporation corresponds to cells cultured without TSA. Data are presented as mean ± SE (n = 6 separate cultures); ^aP < 0.05 vs control cultures, ^cP < 0.05 vs BxPC-3 cells (Wilcoxon’s rank sum test).