Natural epitope variants of the hepatitis C virus impair cytotoxic T lymphocyte activity

doi:10.3748/wjg.v16.i16.1953

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Apr 28, 2010 (publication date) through Feb 2, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2010; 16(16): 1953-1969
Published online Apr 28, 2010. doi: 10.3748/wjg.v16.i16.1953

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Figure 2 Localization of NS3 mutations in the proximity of three cytotoxic T lymphocyte (CTL) epitopes. Sequence alterations within the NS3 region between amino acid (aa) 1060-1198 are graphically visualized. Nonsynonymous (top) and synonymous (bottom) mutations are shown separately. NS3 CTL epitope regions 1073-1081, 1131-1139 and 1169-1177 are indicated.

Citation: Wang S, Buchli R, Schiller J, Gao J, VanGundy RS, Hildebrand WH, Eckels DD. Natural epitope variants of the hepatitis C virus impair cytotoxic T lymphocyte activity. World J Gastroenterol 2010; 16(16): 1953-1969
URL: https://www.wjgnet.com/1007-9327/full/v16/i16/1953.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i16.1953