LOH analysis of genes around D4S2964 identifies ARD1B as a prognostic predictor of hepatocellular carcinoma

Table 4 Multivariate analyses of individual parameters for correlations with overall survival rate: Cox proportional hazards model

Parameter	ARD1B			SEPT11			ARD1B and SEPT11a
	HR	95% CI	P value	HR	95% CI	P value	HR	95% CI	P value
LOH in ARD1B	4.615	1.538-13.851	0.006				4.866	1.528-15.493	0.007
LOH in SEPT11				2.393	1.107-5.170	0.026			0.533
Serum AFP	1.781	0.468-6.774	0.397	2.166	0.748-6.274	0.154			0.208
Tumor size	2.146	0.459-10.033	0.332	3.316	1.001-10.984	0.050			0.393
No. of nodules	6.173	2.072-18.394	0.001	3.002	1.401-6.434	0.005	5.579	1.738-17.904	0.004
Recurrence	0.900	0.305-2.659	0.849	1.707	0.829-3.516	0.147			0.859

^aForward LR method was used. HR: Hazard radio.