Chemotherapy with laparoscope-assisted continuous circulatory hyperthermic intraperitoneal perfusion for malignant ascites

Figure 1 Cancer cells ascites. A: Numerous free cancer cells were found in ascites before circulatory hyperthermic intraperitoneal perfusion chemotherapy (CHIPC) (HE, × 100 ); B: Intact free cancer cells in ascites clearly reduced in number, and some degenerated and necrotized after the first CHIPC (HE, × 100); C: No intact free cancer cells but rather degenerated and necrotized cells were found in ascites after the second CHIPC; D: No free cancer cells were found in ascites after the third CHIPC.