Different profiles of cytokine expression during mild and severe acute pancreatitis

Figure 2 Reduction in number of lymphocytes during severe and necrotizing AP. Number of circulating lymphocytes in peripheral blood was significantly reduced in severe acute pancreatitis (SAP) compared to mild AP groups (0.89 ± 0.08 × 10⁹/L vs 1.18 ± 0.07 × 10⁹/L, P < 0.05), and in necrotizing compared to edematous pancreatitis groups (0.94 ± 0.08 × 10⁹/L vs 1.13 ± 0.08 × 10⁹/L, P < 0.05). These findings demonstrate the presence of possible common molecular pathways leading to the development of severe and necrotizing AP.