Natural taurine promotes apoptosis of human hepatic stellate cells in proteomics analysis

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Apr 21, 2010 (publication date) through Jan 18, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 21, 2010; 16(15): 1916-1923
Published online Apr 21, 2010. doi: 10.3748/wjg.v16.i15.1916

Table 2 Functional categorization of differentially expressed proteins

GO number	Functional description	Proportion (%)	Protein	P value	FDR value
Apoptosis-related
51093	Negative regulation of developmental process	32	TPT1\|ANXA1\|HSPB1\|GLO1\|PRDX2\|SOD1	2.20E-6	2.61E-4
42981	Regulation of apoptosis	32	TPT1\|ANXA1\|HSPB1\|GLO1\|PRDX2\|SOD1	3.19E-5	1.49E-3
43067	Regulation of programmed cell death	32	TPT1\|ANXA1\|HSPB1\|GLO1\|PRDX2\|SOD1	3.45E-5	1.49E-3
Oxidation reaction-related
42542	Response to hydrogen peroxide	16	PRDX3\|SOD1\|PARK7	4.28E-6	4.07E-4
6979	Response to oxidative stress	21	PRDX2\|PRDX3\|SOD1\|PARK7	8.18E-6	5.65E-4
302	Response to reactive oxygen species	16	PRDX3\|SOD1\|PARK7	8.33E-6	5.65E-4
Metabolism-related
44248	Cellular catabolic process	37	PSMB6\|AKR1A1\|PSMD10\|ECHS1\|PRDX3\|SOD1\|MDH1	9.67E-6	5.74E-4
9056	Catabolic process	37	PSMB6\|AKR1A1\|PSMD10\|ECHS1\|PRDX3\|SOD1\|MDH1	3.12E-5	1.49E-3
42743	Hydrogen peroxide metabolic process	11	PRDX3\|SOD1	2.45E-4	9.69E-3

Hypergeometric test, FDR < 0.01. GO: Gene ontology.

Citation: Deng X, Liang J, Lin ZX, Wu FS, Zhang YP, Zhang ZW. Natural taurine promotes apoptosis of human hepatic stellate cells in proteomics analysis. World J Gastroenterol 2010; 16(15): 1916-1923
URL: https://www.wjgnet.com/1007-9327/full/v16/i15/1916.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i15.1916