Inflammatory cytokine gene polymorphisms increase the risk of atrophic gastritis and intestinal metaplasia

Table 1 Parameters of patients with or without progression n (%)

	No progression group (n = 137)	Group I (n = 134)	P value	Group II (n = 101)	P value
Age (yr)
≤ 40	32 (23.4)	45 (33.6)a	0.045	35 (34.7)b	0.027
40-50	76 (55.5)	60 (44.8)		42 (41.6)
≥ 50	29 (21.1)	29 (21.6)	0.330	24 (23.7)	0.200
mean ± SD	44.2 ± 0.7	43.8 ± 0.6		46.7 ± 0.7
Sex			0.600		0.260
Male	59 (43.1)	62 (45.9)		51 (50.5)
Female	78 (56.9)	72 (54.1)		50 (49.5)
H. pylori infection			< 0.001		0.100
Negative	59 (43.1)	30 (22.4)		33 (32.7)
Positive	78 (56.9)	104 (77.6)c		68 (67.3)

^aP = 0.045 vs patients at the age of 40-50 years (χ² = 4.04);

^bP = 0.027 vs patients at the age of 40-50 years (χ² = 4.87);

^cP < 0.001 vs patients with no progression (χ² = 13.13). H. pylori: Helicobacter pylori.