NOD2/CARD15, ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn&rsquo;s disease

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Apr 14, 2010 (publication date) through Mar 2, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 14, 2010; 16(14): 1753-1758
Published online Apr 14, 2010. doi: 10.3748/wjg.v16.i14.1753

Table 1 Demographics and clinical features of patients with CD (mean ± SD) n (%)

	Childhood-onset CD (n = 110)	Adult-onset CD (n = 364)
Sex (male/female)	60/50	178/186
Age of diagnosis (yr)	11.5 ± 4.8	28.99 ± 14.22
Family history in first-degree relative	8 (7.27)	12 (3.29)
Smoking habit
Never		146 (40.11)
Ex-smoker		32 (8.79)
Current		186 (51.10)
Localization of disease
Ileitis	21 (19.09)	121 (33.24)
Colitis	29 (26.36)	38 (10.50)
Ileocolitis	48 (43.64)	187 (51.38)
Upper gastroenteric	12 (10.91)	18 (4.94)
Disease features
Inflammatory	78 (70.91)	223 (61.26)
Stricturing	20 (18.18)	99 (27.20)
Fistulizing	12 (10.91)	42 (11.54)
Extraintestinal manifestations	21 (19.09)	58 (15.93)

CD: Crohn’s disease.

Citation: Gazouli M, Pachoula I, Panayotou I, Mantzaris G, Chrousos G, Anagnou NP, Roma-Giannikou E. NOD2/CARD15, ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn’s disease. World J Gastroenterol 2010; 16(14): 1753-1758
URL: https://www.wjgnet.com/1007-9327/full/v16/i14/1753.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i14.1753