Effectiveness of narrow-band imaging magnification for invasion depth in early colorectal cancer

Table 3 Assessment of the carcinomatous invasion depth based on microvascular architecture

Microvascular architecture	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)	Accuracy (%)
Vessel density	33/43	68/69	0.97 (0.85-0.99)	0.87 (0.78-0.94)	90.2
Non-dense	0.77 (0.61-0.88)	0.99 (0.92-0.99)
Vessel regularity	38/43	61/69	0.83 (0.69-0.92)	0.92 (0.83-0.97)	88.4
Negative	0.88 (0.75-0.96)	0.88 (0.78-0.95)
Caliber regularity	42/43	25/69	0.49 (0.38-0.60)	0.96 (0.80-0.99)	59.8
Negative	0.98 (0.88-0.99)	0.36 (0.25-0.49)
Vessel length	37/43	49/69	0.65 (0.51-0.77)	0.89 (0.78-0.96)	76.8
Short	0.86 (0.84-0.99)	0.71 (0.59-0.81)
Meandering	41/43	20/69	0.46 (0.35-0.56)	0.91 (0.71-0.99)	54.5
Positive	0.95 (0.84-0.99)	0.29 (0.19-0.41)
Caliber	41/43	7/69	0.40 (0.30-0.50)	0.78 (0.40-0.97)	42.9
Wide	0.95 (0.84-0.99)	0.10 (0.04-0.20)

PPV: Positive predictive value; NPV: Negative predictive value.