Effects of thymidine phosphorylase on tumor aggressiveness and 5-fluorouracil sensitivity in cholangiocarcinoma

Figure 4 Knockdown of TP decreases the formation of tube-like structures in an ECM gel angiogenesis assay. Serum of endometriosis patients was used as a positive control (A), and PBS as a negative control (B). Total protein of control (siCtr) (C), TP-deficient (siTP) (D), or WT cells (E and F) were assayed. The tube length was quantified (G).