Perfusion magnetic resonance imaging of the liver

Figure 5 Schematic diagram illustrating a dual-input dual-compartment tracer kinetic model. Dual blood supply carrying gadolinium contrast molecules (blue spheres) from the hepatic artery (F_A) and portal vein (F_PV) enters the hepatic sinusoids (intravascular space). From here, the contrast molecules can leak outwards into the Space of Disse (interstitial space). Using a dual-input, dual compartment tracer kinetic model allows the estimation of intravascular properties (e.g. blood flow, F), as well as characteristics of the interstitial space (e.g. PS).