Melatonin and Doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines

Figure 6 Effect of Melatonin and/or Doxorubicin on the expression of Casepase-3 in HepG2 (A) and Bel-7402 cells (B), and the quantitative analysis (C) of Caspase-3 expression. A: (a) Untreated cells; (b) 10^-5 mol/LMel; (c) 1.25 mg/L Dox; (d) 10^-5 mol/L Mel plus 1.25 mg/L Dox; B: (a) Untreated cells; (b) 10^-5 mol/L Mel; (c) 2.5 mg/L Dox; (d) 10^-5 mol/L Mel plus 2.5 mg/L Dox. S-P (× 400); C: Quantitative analysis of Caspase-3 expression by Biological Image Analysis System. Data are presented as mean ± SD (error bar). ^fP < 0.01 vs control of Caspase-3, ^hP < 0.01 vs Dox alone.