Effects of ethanol on the proteasome interacting proteins

doi:10.3748/wjg.v16.i11.1349

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Mar 21, 2010 (publication date) through Jul 21, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 21, 2010; 16(11): 1349-1357
Published online Mar 21, 2010. doi: 10.3748/wjg.v16.i11.1349

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Figure 4 Illustration of hypothetical chronic ethanol feeding effects in 26S dysfunction. As a result of phosphorylation deregulation, 20S and 19S binding is altered, which causes 26S dysfunction. Total dephosphorylation of proteasome subunits by phosphatases is prevented by 14-3-3 protein sequestration of the 20S proteasome.

Citation: Bardag-Gorce F. Effects of ethanol on the proteasome interacting proteins. World J Gastroenterol 2010; 16(11): 1349-1357
URL: https://www.wjgnet.com/1007-9327/full/v16/i11/1349.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i11.1349