Alcohol-induced alterations of the hepatocyte cytoskeleton

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Mar 21, 2010 (publication date) through Aug 31, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 21, 2010; 16(11): 1358-1365
Published online Mar 21, 2010. doi: 10.3748/wjg.v16.i11.1358

Table 1 Ethanol-induced changes in cytoskeleton-associated protein gene expression

Gene product	Expression levels	System	EtOH exposure	Ref.
α₁-tubulin	Increased	Rat liver	Chronic (IG)	[1]
β₅-tubulin	Increased	Rat liver	Chronic (IG)	[1]
β-tubulin	Decreased	Rat liver	Chronic	[2]
Kinesin 2c	Increased	Mouse liver	Acute	[3]
Tau	Decreased	Rat liver	Chronic	[2]
α_E integrin	Increased	Rat liver	Chronic (IG)	[4]
PDZ and LIM domain protein 1	Decreased	Rat liver	Chronic	[5]
Thymosin β-like protein	Decreased	Rat liver	Chronic	[2]
Myosin 1b	Decreased	HepG2 (+ CYP2E1)	Acute	[4]
Myosin 1E	Decreased	Rat liver	Chronic	[2]
Myosin light chain 2	Decreased	Rat liver	Chronic	[2]
Myosin light chain 3	Decreased	Rat liver	Chronic	[2]
Titin	Decreased	HepG2 (+ CYP2E1)	Acute	[4]
Myosin VII A and Rab interacting protein 1	Increased	Rat liver	Chronic (IG)	[6]
ZO-2	Decreased	Rat liver	Chronic	[5]
Cadherin 17	Increased	Rat liver	Chronic (IG)	[4]

IG: Intragastric.

Citation: Shepard BD, Tuma PL. Alcohol-induced alterations of the hepatocyte cytoskeleton. World J Gastroenterol 2010; 16(11): 1358-1365
URL: https://www.wjgnet.com/1007-9327/full/v16/i11/1358.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i11.1358