Decreased levels of plasma adiponectin associated with increased risk of colorectal cancer

Table 1 Background of the male patients examined by colonoscopy n (%)

	Control (n = 26)	Adenoma (n = 47)	Early cancer (n = 34)	Advanced cancer (n = 17)	P-value
Age (yr)	67.9 ± 12.4	65.1 ± 11.7	67.0 ± 8.8	66.5 ± 7.8	0.810
Diabetes	1 (3.8)	6 (12.8)	2 (5.9)	2 (11.8)	0.523
Smokers
Current-	9 (34.6)	18 (38.2)	13 (38.2)	7 (41.8)	0.977
Ex-	6 (8.5)	14 (21.7)	10 (15.8)	2 (11.0)	0.480
Alcohol	15 (57.7)	30 (63.8)	27 (79.4)	14 (82.4)	0.151
NSAIDs	2 (7.7)	2 (4.3)	1 (3.0)	0 (0)	0.631
Other meds	6 (23.1)	11 (23.4)	8 (23.5)	3 (17.6)	0.965
BMI (kg/m2)	21.8 ± 3.1	23.2 ± 3.2	24.4 ± 3.8a	22.7 ± 3.8	0.025
BP-S (mmHg)	123 ± 14	129 ± 14	129 ± 13	133 ± 20	0.193
BP-D (mmHg)	76 ± 12	76 ± 10	78 ± 10	81 ± 11	0.331

NSAIDs: Non-steroid anti-inflammatory drug; Other meds: Other medicines such as angiotensin receptor antagonists, angiotensin converting enzyme inhibitors, or HMG-CoA reductase inhibitors; BMI: Body mass index; BP-S: Systolic blood pressure; BP-D: Diastolic blood pressure. Age, BMI, BP-S and BP-D are expressed as the mean ± SD and P-value was evaluated by analysis of variance. BMI was additionally evaluated by Dunnett’s test (^aP = 0.015). Diabetes (without insulin injections), current smoker, ex-smoker, alcohol habit (ethanol intake more than 15 g/d on average) and NSAID users and Other Meds. users are expressed as the number of patients, and P values were evaluated by χ² test.