Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer

Table 8 Comparison of the incidence of gastric non-cardia cancer and peptic ulcer in Asian and Western populations

Disease	Gene	Reference	Genotype	Western			Asian
				OR	95% CI	P value	OR	95% CI	P value
GC	IL-4-590	C/C	C/T	0.57	0.41-0.72	< 0.01	1.12	0.87-1.65	0.28
			T/T	0.40	0.25-0.64	< 0.01	0.43	0.18-1.04	0.06
			T carrier	0.55	0.46-0.67	< 0.01	1.08	0.79-1.45	0.17
	IL-6-572	C/C	C/G	9.87	2.56-37.98	< 0.01	0.85	0.61-1.19	0.34
			G/G	21.13	5.56-131.98	< 0.01	0.99	0.48-2.03	0.97
			G carrier	13.32	3.64-48.69	< 0.01	0.87	0.63-1.20	0.38
	IL-8-251	T/T	T/A	1.04	0.86-1.25	0.69	1.06	0.93-1.20	0.38
			A/A	1.04	0.83-1.31	0.73	0.95	0.79-1.14	0.56
			A carrier	1.04	0.87-1.24	0.67	1.03	0.92-1.16	0.61
GU	IL-4-590	C/C	C/T	0.61	0.35-1.05	0.08
			T/T	0.30	0.07-1.24	0.10
			T carrier	0.55	0.32-0.94	0.03
	IL-6-572	C/C	C/G	1.31	0.07-2.56	0.42	0.77	0.55-1.05	0.07
			G/G	2.98	1.05-8.47	0.04	0.67	0.33-1.34	2.66
			G carrier	1.65	0.89-3.04	1.65	0.74	0.55-1.01	0.06
	IL-8-251	T/T	T/A	1.48	1.12-1.97	< 0.01	1.11	0.93-1.31	0.25
			A/A	1.53	1.09-2.14	0.01	0.87	0.67-1.14	0.31
			A carrier	1.49	1.14-1.96	< 0.01	1.05	0.89-1.24	0.55