Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer

Table 7 Prevalence of inflammatory cytokine gene genotypes in East Asian and Western populations

Gene	Population	NUD			GC			PU
IL-2-330		T/T	T/G	G/G	T/T	T/G	G/G	T/T	T/G	G/G
	Asian	870	755	153	258	209	35	159	45	16
	Western
IL-4-590		C/C	C/T	T/T	C/C	C/T	T/T	C/C	C/T	T/T
	Asian	268	105	19	229	107	7
	Western	1448	934	210	362	135	21
IL-6-174		C/C	C/G	G/G	C/C	C/G	G/G	C/C	C/G	G/G
	Asian				0	0	30	0	0	30
	Western	126	310	261	34	82	112	1	26	94
IL-6-572		C/C	C/G	G/G	C/C	C/G	G/G	C/C	C/G	G/G
	Asian	140	123	15	170	126	18	165	170	19
	Western	37	20	5	3	16	11	62	34	25
IL-6-597		G/G	G/A	A/A	G/G	G/A	A/A	G/G	G/A	A/A
	Asian				30	0	0	30	0	0
	Western	102	102	61	45	67	28	75	37	10
IL-8-251		T/T	T/A	A/A	T/T	T/A	A/A	T/T	T/A	A/A
	Asian	1324	1425	443	735	826	233	294	350	86
	Western	676	1093	449	243	418	168	76	182	77
IL-8+396		T/T	T/G	G/G	T/T	T/G	G/G	T/T	T/G	G/G
	Asian	152	181	69
	Western	72	112	24	27	43	12
IL-8+781		C/C	C/T	T/T	C/C	C/T	T/T	C/C	C/T	T/T
	Asian	167	177	62
	Western	81	105	22	29	41	11