Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer

Table 1 Association of IL-2 polymorphism and gastroduodenal diseases

Position	Disease	Authors	Year		n
-330 T/G						T/T	T/G	G/G
	GC	Wu et al[37]	2009	GC	1026	491	441	94	GCC: T/T: 0.7 (0.4-1.0)
				NUD	1083	516	480	87
	GC	Shin et al[35]	2008	GC	122	79	35	8	NS
				NUD	100	72	16	12
	PU	Shin et al[35]	2008	PU	220	159	45	16	NS
				NUD	100	72	16	12
	Atrophy	Togawa et al[34]	2005	Atrophy	152	80	63	9	T/T: 2.8 (1.3-6.2)
				NUD	443	202	196	45
-384 G/T						G/G	G/T	T/T
	GCC	Savage et al[36]	2004	GC	87	16	47	20	NS
				NUD	379	96	174	109
+114 G/T						G/G	G/T	T/T
	GCC	Savage et al[36]	2004	GC	82	33	35	14	NS
				NUD	377	149	148	80

GC: Gastric cancer; GCC: Gastric cardia cancer; PU: Peptic ulcer; IL: Interleukin; NUD: Non-ulcer dyspepsia; NS: Not significant.