Atrial natriuretic peptide signal pathway upregulated in stomach of streptozotocin-induced diabetic mice

Figure 1 Comparision of gastric contractility and expression of ICCs in normal and STZ-induced diabetic mice. A: Representative traces of spontaneous gastric contraction in control and STZ-induced diabetic mice; B: Summary of amplitudes and frequencies of gastric motility in control and STZ-induced diabetic groups (n = 8; ^aP < 0.05 vs control group); C and D: Expression of c-Kit-positive cells in the muscle layer. Arrow indicates the positive staining area. Expression of c-Kit was more obvious in STZ-induced diabetic mice than in the normal controls. Scale bar = 40 μm.