Aminoguanidine impedes human pancreatic tumor growth and metastasis development in nude mice

Table 1 AG enlarges tumor volume doubling time (mean ± SD)

Treatment	Doubling time (d)
Control	7.8 ± 0.3
AG 1 mg/mL	7.8 ± 0.3
AG 2 mg/mL	10.0 ± 0.5a
AG 4 mg/mL	11.1 ± 0.7a

Tumor volume doubling times were obtained by non linear fit of tumor growth rate (shown in Figure 1) to an exponential growth equation.

^aP < 0.01 vs control and AG 1 mg/mL, ANOVA one way with Bonferroni post test.