A rabbit model of pediatric nonalcoholic steatohepatitis: The role of adiponectin

Table 1 Comparison of indexes among three groups

	Control (n = 10)	Group A (n = 11)	Group B (n = 11)
BW (g)	809.0 ± 58.0 (625-1067)	973.0 ± 86.39 (545-1350)	816.1 ± 67.5 (545-1200)
WG (g)	928.0 ± 58.1 (570-1268)	1097.2 ± 72.3a (779.0-1485)	1360.5 ± 107.6c (537-1795)
LW (g)	54.4 ± 1.71 (47-67.5)	93.81 ± 6.64b (62.2-121.9)	104.6 ± 4.42b (74.4-123.5)
Liver index	0.032 ± 0.001 (0.02-0.04)	0.045 ± 0.002a (0.03-0.06)	0.051 ± 0.005a (0.04-0.1)
Adiponectin (&mgr;g/L)	27.36 ± 7.29 (18.14-39.55)	21.87 ± 4.84a (12.12-28.47)	21.48 ± 4.60a (16.71-32.16)
ALT/AST	1.00 ± 0.62	0.73 ± 0.38	0.70 ± 0.1
Lg (ALT)	1.60 ± 0.17	1.9 ± 0.29b	1.84 ± 0.28b
Lg (AST)	1.67 ± 0.18	2.08 ± 0.31b	2.15 ± 0.30b
Lg (TC)	0.24 ± 0.16	1.56 ± 0.46b	1.56 ± 0.96b
Lg (TG)	0.00 ± 0.16	1.03 ± 0.24b	1.16 ± 0.33b
Lg (IL-10)	2.26 ± 0.24	1.72 ± 0.38b	1.83 ± 0.39b
Lg (IL-6)	1.41 ± 0.33	1.38 ± 0.42	1.86 ± 0.21bd
Lg (INF-α)	0.66 ± 0.08	0.86 ± 0.43	1.18 ± 0.07bc

Group A: 8 wk model; Group B: 12 wk model. Compared with control,

^aP < 0.05,

^bP < 0.01. Compared with group A,

^cP < 0.05,

^dP < 0.01. BW: Body weight; WG: Weight gain; LW: Liver weight.