Establishment of an animal model of ischemic type intrahepatic biliary lesion in rabbits

Table 1 The change of biochemical indexes of rabbits in all groups (mean ± SD )

Groups	Preoperation	1 d post-operation	1 wk post-operation	2 wk post-operation	3 wk post-operation	4 wk post-operation
AST (U/L)
SO	38.3 ± 2.4	38.1 ± 2.6	38.0 ± 2.4	38.7 ± 2.3	38.5 ± 2.1	39.1 ± 3.3
ABO-1 h	38.2 ± 2.3	260.3 ± 19.51	85.0 ± 11.11	39.0 ± 1.6	38.2 ± 2.5	39.0 ± 3.3
ABO-2 h	40.1 ± 1.7	359.9 ± 11.92	154.8 ± 14.42	86.9 ± 5.72	39.1 ± 1.7	38.8 ± 1.9
ABO-3 h	39.8 ± 4.6	461.9 ± 11.43	199.2 ± 16.93	112.0 ± 16.73	82.7 ± 9.73	40.1 ± 3.6
ALT (U/L)
SO	42.2 ± 2.2	42.0 ± 2.3	43.2 ± 2.0	40.0 ± 3.7	40.7 ± 3.4	42.0 ± 2.3
ABO-1 h	42.0 ± 2.4	200.5 ± 13.01	169.8 ± 14.31	65.9 ± 11.51	42.3 ± 2.8	43.2 ± 2.0
ABO-2 h	43.9 ± 2.3	400.1 ± 12.32	200.2 ± 12.02	92.2 ± 8.62	42.7 ± 3.1	42.2 ± 3.7
ABO-3 h	43.8 ± 4.6	505.9 ± 14.03	292.0 ± 15.83	116.6 ± 9.03	87.7 ± 8.83	44.6 ± 2.5
ALP (U/L)
SO	117.0 ± 14.7	115.9 ± 15.9	114.3 ± 14.8	110.3 ± 9.6	113.3 ± 12.7	111.4 ± 11.7
ABO-1 h	117.6 ± 14.5	203.9 ± 18.81	139.8 ± 10.31	119.6 ± 9.01	112.5 ± 9.3	109.5 ± 7.5
ABO-2 h	118.8 ± 14.2	304.8 ± 16.82	173.1 ± 11.22	136.2 ± 6.62	138.8 ± 6.32	139.6 ± 7.42
ABO-3 h	113.9 ± 11.7	440.0 ± 29.43	226.0 ± 13.73	183.7 ± 9.83	149.4 ± 10.23	149.7 ± 11.53
GGT (U/L)
SO	16.7 ± 2.1	17.5 ± 2.5	18.0 ± 2.1	18.5 ± 2.6	18.8 ± 3.9	17.3 ± 2.3
ABO-1 h	18.7 ± 2.2	62.8 ± 10.21	20.3 ± 3.4	17.3 ± 2.8	19.7 ± 3.5	17.5 ± 2.5
ABO-2 h	17.7 ± 2.8	111.5 ± 9.22	106.5 ± 11.32	81.9 ± 7.62	84.7 ± 9.42	59.6 ± 13.62
ABO-3 h	17.9 ± 3.0	214.6 ± 18.63	182.5 ± 8.63	153.7 ± 14.43	155.9 ± 19.33	98.0 ± 6.83
TBIL (&mgr;mol/L)
SO	10.0 ± 2.0	9.5 ± 1.7	10.4 ± 2.0	10.1 ± 1.9	10.6 ± 2.2	10.8 ± 2.3
ABO-1 h	10.1 ± 1.8	21.0 ± 3.11	10.6 ± 2.4	9.8 ± 1.6	9.5 ± 2.0	10.5 ± 2.3
ABO-2 h	9.9 ± 2.2	30.7 ± 2.32	19.8 ± 1.92	10.5 ± 2.2	9.3 ± 1.5	9.9 ± 2.0
ABO-3 h	9 .7 ± 1.9	40.7 ± 4.33	30.6 ± 2.43	18.1 ± 2.23	10.3 ± 1.8	11.2 ± 2.3
DBIL (&mgr;mol/L)
SO	3.9 ± 1.0	3.8 ± 1.5	3.9 ± 1.3	4.9 ± 1.6	4.5 ± 1.1	5.5 ± 1.2
ABO-1 h	4.7 ± 1.3	13.5 ± 2.51	4.2 ± 1.3	4.8 ± 0.8	4.1 ± 1.2	4.6 ± 0.8
ABO-2 h	4.3 ± 1.3	20.4 ± 2.82	13.4 ± 2.22	4.9 ± 1.1	3.9 ± 1.1	4.6 ± 1.3
ABO-3 h	4.5 ± 1.1	33.7 ± 3.03	19.6 ± 1.73	11.2 ± 2.03	5.0 ± 1.4	4.8 ± 1.5

¹ABO-1 h vs SO, P < 0.05;

²ABO-2 h vs ABO-1 h, P < 0.05;

³ABO-3 h vs ABO-2 h, P < 0.05.