Elevated pro-inflammatory and lipotoxic mucosal lipids characterise irritable bowel syndrome

Table 2 The 15 lipids with the largest and most significant differences between patients and controls

Lipid name	Fold (IBS/healthy control)	P value1	FDR Q value
Cer (d18:1/24:1)	1.3	0.001	0.022
Cer (d18:1/24:2)	1.4	0.00004	0.0018
DG (36:2)	1.9	0.000001	0.0003
GlycoSL (m/z = 1199.805)	1.9	0.001	0.018
GlycoSL (m/z = 1195.851)	2.0	0.0003	0.0069
lysoPC (16:0)	2.1	0.00006	0.0020
lysoPC (18:0)	1.9	0.0002	0.0049
lysoPC (18:1)	2.8	0.00002	0.0013
lysoPE (18:1e)	2.4	0.00002	0.0013
7TG (46:5)	1.4	0.04	0.19
TG (48:5)	1.6	0.03	0.17
TG (48:6)	1.7	0.03	0.18
TG (49:3)	2.1	0.009	0.089
TG (51:4)	1.6	0.04	0.19
TG (51:5)	1.8	0.02	0.12

¹Wilcoxon rank sum test. Cer: Ceramide; DG: Diacylglycerol; GlycoSL: Glycosphingolipid; lysoPC: Lysophosphatidylcholine; lysoPE: Lysophosphatidylethanolamine; TG: Triacylglycerol.