Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer

Table 2 Clinicopathological characteristics of 122 patients with gastric cancer n (%)

	All	T393C genotypes			P
		CC	CT	TT
n (%)	122 (100)	39 (32)	57 (46.7)	26 (21.3)
Gender
Male	78 (63.9)	25 (32.1)	34 (43.6)	19 (24.4)
Female	44 (36.1)	14 (31.8)	23 (52.3)	7 (15.9)	0.274
WHO
Papillary/Tubular/Mucinous	76 (62.3)	23 (30.3)	34 (44.7)	19 (25)
Signet-ring cancer	38 (31.1)	12 (31.6)	19 (50)	7 (18.4)
Other	8 (6.6)	4 (50)	4 (50)	0	0.340
Differentiation
Well/Moderate (G1-G2)	42 (34.4)	12 (28.6)	22 (52.4)	8 (19)
Poor (G3-G4)	80 (65.6)	27 (33.8)	35 (43.8)	18 (22.5)	0.805
Laurén
Intestinal	52 (42.6)	16 (30.8)	25 (48.1)	11 (21.2)
Diffuse	55 (45.1)	17 (30.9)	29 (52.7)	9 (16.4)
Mixed	15 (12.3)	6 (40)	3 (20)	6 (40)	0.171
Ming
Expanding	47 (38.5)	14 (29.8)	24 (51.1)	9 (19.1)
Infiltrative	75 (61.5)	25 (33.3)	33 (44)	17 (22.7)	0.620
pT-category
T1	30 (24.6)	7 (23.3)	13 (43.3)	10 (33.3)
T2	44 (36.1)	12 (27.3)	22 (50)	10 (22.7)
T3	38 (31.1)	14 (36.8)	18 (47.4)	6 (15.8)
T4	10 (8.2)	6 (60)	4 (40)	0	0.110
pN-category
N0	49 (40.2)	11 (22.4)	24 (49)	14 (28.6)
N1	34 (27.9)	13 (38.2)	13 (38.2)	8 (23.5)
N2	14 (11.5)	6 (42.9)	6 (42.9)	2 (14.3)
N3	25 (20.5)	9 (36)	14 (56)	2 (8)	0.196
pM-category
M0	99 (81.1)	30 (30.3)	45 (45.5)	24 (24.2)
M1	23 (18.9)	9 (39.1)	12 (52.2)	2 (8.7)	0.101
R-category
R0	118 (96.7)	38 (32.5)	54 (46.2)	25 (21.4)
R1/R2	4 (3.3)	1 (25)	2 (50)	1 (25)	0.950
UICC stage
Ia	26 (21.3)	5 (19.2)	11 (42.3)	10 (38.5)
Ib	22 (18)	7 (31.8)	12 (54.5)	3 (13.6)
II	18 (14.8)	4 (22.2)	7 (38.9)	7 (38.9)
IIIa	11 (9)	4 (36.4)	5 (45.5)	2 (18.2)
IIIb	4 (3.3)	2 (50)	2 (50)	0
IV	41 (33.6)	17 (41.5)	20 (48.8)	4 (9.8)	0.023

P values are given for dichotomization between C+ (CC+CT) and C- (TT) genotypes.