Identification of TRPM7 channels in human intestinal interstitial cells of Cajal

Figure 2 Effects of flufenamic acid, 2-aminoethoxydiphenyl borate (2-APB) and La³⁺ on electrical responses. Flufenamic acid (50 μmo/L, A), 2-APB (50 μmo/L, B) or La³⁺ (50 μmo/L, C) were applied while recording electrical activity of isolated smooth muscles of the human colon. All drugs inhibited the spontaneous electrical activity; D: The histograms summarize the frequency of spontaneous electrical activities in human colon with flufenamic acid, 2-APB, and La³⁺. ^bP < 0.01.