Role of the receptor for advanced glycation end products in hepatic fibrosis

Figure 3 Advanced glycation end product-bovine serum albumin (AGE-BSA) (A), N^ε-(carboxymethyl) lysine (CML)-BSA (B) and tumor necrosis factor (TNF)-α (C) upregulate RAGE protein expression in hepatic stellate cells. Mean RAGE protein expression as determined by quantitative Western blotting from extracts of rat HSC lines relative to β-actin. Cells were incubated for 24 h and results are derived from at least three independent experiments and expressed as mean ± SD. Data are shown as x-fold increase compared to cells incubated with BSA alone. ^aP < 0.05, ^bP < 0.01, ^dP < 0.001 vs BSA.