Nicotinamide overload may play a role in the development of type 2 diabetes

doi:10.3748/wjg.15.5674

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Dec 7, 2009 (publication date) through Nov 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 7, 2009; 15(45): 5674-5684
Published online Dec 7, 2009. doi: 10.3748/wjg.15.5674

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Figure 2 Plasma N¹-methylnicotinamide levels of diabetic and non-diabetic subjects after nicotinamide loading. A: Representative HPLC chromatograms of plasma N¹-methylnicotinamide levels from a non-diabetic (a, b) and a diabetic (c, d) subject before (a, c) and 5 h after (b, d) 100 mg nicotinamide loading. 1: N¹-methylnicotinamide; 2: Internal standard: N¹-methylnicotinamide; B: Summary of the results from the measurements shown in A. Bar graph indicates mean ± SD.

Citation: Zhou SS, Li D, Sun WP, Guo M, Lun YZ, Zhou YM, Xiao FC, Jing LX, Sun SX, Zhang LB, Luo N, Bian FN, Zou W, Dong LB, Zhao ZG, Li SF, Gong XJ, Yu ZG, Sun CB, Zheng CL, Jiang DJ, Li ZN. Nicotinamide overload may play a role in the development of type 2 diabetes. World J Gastroenterol 2009; 15(45): 5674-5684
URL: https://www.wjgnet.com/1007-9327/full/v15/i45/5674.htm
DOI: https://dx.doi.org/10.3748/wjg.15.5674