A simple taurocholate-induced model of severe acute pancreatitis in rats

doi:10.3748/wjg.15.5732

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Dec 7, 2009 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 7, 2009; 15(45): 5732-5739
Published online Dec 7, 2009. doi: 10.3748/wjg.15.5732

Table 2 Pancreatitis pathology score

Groups (n = 8)	Score
Groups (n = 8)	Interstitial edema	Leukocyte infiltration	Acinar cell necrosis	Hemorrhage	Total
Control
4 d	0.13 ± 0. 33	0.13 ± 0.33	0	0	0.25 ± 0.67
7 d	0.13 ± 0.33	0	0	0	0.13 ± 0.33
SAP
4 d	1.5 ± 0.76^a	2.38 ± 0.74^a	1.75 ± 0.71^a	0.75 ± 1.17^a	6.38 ± 2.20^a
7 d	1.25 ± 0.46^b	2.13 ± 0.99^b	1.5 ± 0.54^b	0.50 ± 1.07^b	5.38 ± 1.77^b

In this table, the pancreatitis pathology scores in severe acute pancreatitis (SAP) rats were significantly higher than in control rats in every single aspect as well as the total score, both on the 4th day (^aP < 0.01) and on the 7th day (^bP < 0.01).

Citation: Liu ZH, Peng JS, Li CJ, Yang ZL, Xiang J, Song H, Wu XB, Chen JR, Diao DC. A simple taurocholate-induced model of severe acute pancreatitis in rats. World J Gastroenterol 2009; 15(45): 5732-5739
URL: https://www.wjgnet.com/1007-9327/full/v15/i45/5732.htm
DOI: https://dx.doi.org/10.3748/wjg.15.5732