Glutathione-S-transferase (GSTM1, GSTT1) and the risk of gastrointestinal cancer in a Korean population

Table 3 GST (M1, T1) genotypes in relation of CRC risk stratified by some factors

	GSTM1 (null)		GSTT1 (null)
	OR (95% CI)	Pa	OR (95% CI)	Pa
All case	1.065 (0.923-1.228)		1.041 (0.903-1.200)
Smoking
Never smoker	1.040 (0.822-1.316)		0.999 (0.790-1.262)
Ever smoker	1.077 (0.889-1.304)	0.907	1.067 (0.882-1.291)	0.659
Drinking
Never drinkers	1.025 (0.845-1.243)		1.052 (0.868-1.275)
Current drinkers	1.170 (0.928-1.475)	0.426	1.084 (0.862-1.364)	0.870
Age (yr)
≤ 65	1.061 (0.890-1.265)		1.054 (0.885-1.256)
> 65	1.070 (0.835-1.370)	0.999	1.039 (0.811-1.330)	0.901
TNM stage
0+I+II	1.054 (0.882-1.261)		1.106 (0.926-1.323)
III+IV	1.101 (0.924-1.312)		1.035 (0.870-1.232)
Tumor site
Colon	0.980 (0.822-1.169)		1.090 (0.914-1.300)
Rectum	1.149 (0.970-1.360)		0.996 (0.842-1.178)

Adjusted for age, sex; P^a for P interaction.