A better parameter in predicting insulin resistance: Obesity plus elevated alanine aminotransferase

doi:10.3748/wjg.15.5598

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Nov 28, 2009 (publication date) through Feb 12, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2009; 15(44): 5598-5603
Published online Nov 28, 2009. doi: 10.3748/wjg.15.5598

Table 2 Abnormality prevalence distribution, stratified by HOMA_IRn (%)

	The four sub-groups stratified by HOMA_IR				Total
Abnormality¹	Q1 327 (25)	Q2 326 (25)	Q3 328 (25)	Q4 327 (25)	1308 (100)
Obesity	20 (6.1)	29 (8.9)	81 (24.7)^a	153 (46.8)^a	283 (21.6)
Elevated ALT	25 (7.6)	36 (11.0)	74 (22.6)^a	118 (36.1)^a	253 (19.3)
Metabolic syndrome components
Abdominal obesity	45 (13.8)	74 (22.7)^a	126 (38.4)^a	188 (57.5)^a	433 (33.1)
Elevated blood pressure	110 (33.6)	118 (36.2)	136 (41.5)^a	187 (57.2)^a	551 (42.1)
Elevated fasting glucose	16 (4.9)	22 (6.7)	37 (11.3)^a	62 (19.0)^a	137 (10.5)
Elevated triglyceride	58 (17.7)	83 (25.5)^a	132 (40.2)^a	195 (59.6)^a	468 (35.8)
Hypo-HDL cholesterolemia	39 (11.9)	47 (14.4)	71 (21.6)^a	108 (33.0)^a	265 (20.3)
Alcohol consumption	83 (25.4)	56 (17.2)	74 (22.6)	73 (22.3)	286 (21.9)
Cigarette smoking	122 (37.3)	118 (36.2)^a	108 (32.9)	109 (33.3)	457 (34.9)

¹Obesity: Body mass index ≥ 27 kg/m²; Elevated ALT: ALT > 40 U/L; Abdominal obesity: waist circumference ≥ 90 cm in male adults; Elevated blood pressure: blood pressure ≥ 130/85 mmHg; Elevated fasting glucose: fasting glucose ≥ 100 mg/dL; Elevated triglyceride: triglyceride ≥ 150 mg/dL; Hypo-HDL cholesterolemia: HDL cholestero1 < 40 mg/dL; Hypercholesterolemia: total cholesterol ≥ 200 mg/dL; Elevated LDL: LDL cholesterol ≥ 130 mg/dL; Alcohol consumption: more than once per week; Cigarette smoking: more than one pack per day.

^aP < 0.05 vs Q1 (χ² test).

Citation: Chen PH, Chen JD, Lin YC. A better parameter in predicting insulin resistance: Obesity plus elevated alanine aminotransferase. World J Gastroenterol 2009; 15(44): 5598-5603
URL: https://www.wjgnet.com/1007-9327/full/v15/i44/5598.htm
DOI: https://dx.doi.org/10.3748/wjg.15.5598