Genome-wide association studies - A summary for the clinical gastroenterologist

Figure 1 Example of cluster plots for two SNPs. Plot A shows the plotting of the normalized intensity values for a SNP with good clustering. Each color represents the respective genotype (blue for GG, green for AG and red for AA). Plot B demonstrates the cluster plot for a SNP with bad clustering (same color coding as in A). Disease-associated SNPs demonstrating cluster plots as in B should be discarded as the significant associations at such SNPs are most likely technical artifacts.