CDH1 promoter polymorphism (-347G→GA) is a possible prognostic factor in sporadic colorectal cancer

Figure 3 E-cadherin expression in colon tissues of different types. A: E-cadherin expression is significantly higher in normal controls than in CRC patients (t-test, P < 0.001); B: E-cadherin expression is significantly higher in well differentiated CRC patients than in poorly differentiated CRC patients (t-test, P = 0.001); C: There is no significant difference in E-cadherin expression between the G-allele and GA-allele in normal controls (t-test, P = 0.292). However, E-cadherin expression is significantly higher for the G-allele than for the GA-allele in CRC patients (t-test, P = 0.018).