Experimental evidence of obesity as a risk factor for severe acute pancreatitis

Figure 2 Mediators involved in the pathogenesis of acute pancreatitis. After the acinar cell injury occurs, inflammatory cells will synthesize and release proinflammatory cytokines and chemokines that induce systemic effects (vascular leakage, etc.). All these consequences will finally dictate the occurrence of pancreatic necrosis and abscess.