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©2009 The WJG Press and Baishideng.
World J Gastroenterol. Nov 14, 2009; 15(42): 5326-5333
Published online Nov 14, 2009. doi: 10.3748/wjg.15.5326
Published online Nov 14, 2009. doi: 10.3748/wjg.15.5326
Table 7 Sensitivity, specificity, positive and negative predictive values of various histological features in differentiating non-biliary atresia from biliary atresia
| Histological features | Non-BA | BA | Sensitivity for BA (%) | Specificity for BA (%) | Positive PV for non-BA & negative PV for BA (%) | Negative PV for non-BA & positive PV for BA (%) |
| Lymphocytic infiltration | ||||||
| Moderate to severe | 23 | 7 | 23/50 (46) | 26/33 (79) | 23/30 (77) | 26/53 (49) |
| Absent or mild | 27 | 26 | ||||
| Neutrophilic infiltration | ||||||
| Moderate to severe | 15 | 3 | 15/50 (30) | 30/33 (91) | 15/18 (83) | 30/65 (46) |
| Absent to mild | 35 | 30 | ||||
| Giant cell transformation of hepatocytes | ||||||
| Diffuse | 16 | 1 | 16/50 (32) | 32/33 (97) | 16/17 (94) | 32/66 (48) |
| None or around central vein | 34 | 32 | ||||
| Hepatocytes swelling | ||||||
| Periportal or diffuse | 27 | 4 | 27/50 (54) | 29/33 (88) | 27/31 (87) | 29/52 (56) |
| None or mild/focal | 23 | 29 | ||||
- Citation: Lee WS, Looi LM. Usefulness of a scoring system in the interpretation of histology in neonatal cholestasis. World J Gastroenterol 2009; 15(42): 5326-5333
- URL: https://www.wjgnet.com/1007-9327/full/v15/i42/5326.htm
- DOI: https://dx.doi.org/10.3748/wjg.15.5326